| Reference | </br>1:Sofalcone upregulates the nuclear factor (erythroid-derived 2)-like 2/heme oxygenase-1 pathway, reduces soluble fms-like tyrosine kinase-1, and quenches endothelial dysfunction: potential therapeutic for preeclampsia. Onda K, Tong S, Nakahara A, Kondo M, Monchusho H, Hirano T, Kaitu/’u-Lino T, Beard S, Binder N, Tuohey L, Brownfoot F, Hannan NJ.Hypertension. 2015 Apr;65(4):855-62. doi: 10.1161/HYPERTENSIONAHA.114.04781. Epub 2015 Feb 9. PMID: 25667213 Free Article</br>2:Quantification of sofalcone in human plasma and urine by high performance liquid chromatography-mass spectrometry. Wang L, Song L, Jiang X.J Pharm Biomed Anal. 2011 Jul 15;55(5):1179-85. doi: 10.1016/j.jpba.2011.03.040. Epub 2011 Apr 6. PMID: 21530127 </br>3:Sofalcone, a gastroprotective drug, promotes gastric ulcer healing following eradication therapy for Helicobacter pylori: a randomized controlled comparative trial with cimetidine, an H2-receptor antagonist. Higuchi K, Watanabe T, Tanigawa T, Tominaga K, Fujiwara Y, Arakawa T.J Gastroenterol Hepatol. 2010 May;25 Suppl 1:S155-60. doi: 10.1111/j.1440-1746.2010.06232.x. PMID: 20586860 </br>4:Sofalcone, a gastric mucosa protective agent, increases vascular endothelial growth factor via the Nrf2-heme-oxygenase-1 dependent pathway in gastric epithelial cells. Shibuya A, Onda K, Kawahara H, Uchiyama Y, Nakayama H, Omi T, Nagaoka M, Matsui H, Hirano T.Biochem Biophys Res Commun. 2010 Jul 30;398(3):581-4. doi: 10.1016/j.bbrc.2010.06.124. Epub 2010 Jul 3. PMID: 20599750 </br>5:Sofalcone, an anti-ulcer chalcone derivative, suppresses inflammatory crosstalk between macrophages and adipocytes and adipocyte differentiation: implication of heme-oxygenase-1 induction. Tanaka H, Nakamura S, Onda K, Tazaki T, Hirano T.Biochem Biophys Res Commun. 2009 Apr 17;381(4):566-71. doi: 10.1016/j.bbrc.2009.02.086. Epub 2009 Feb 23. PMID: 19239904 </br>6:Analysis of sofalcone in human plasma by high performance liquid chromatography. Wen A, Wang Z, Hang T, Jia Y, Zhang T, Wu Y, Gao X, Yang Z.J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Sep 1;856(1-2):348-52. Epub 2007 May 26. PMID: 17586104 </br>7:Sofalcone, a mucoprotective agent, increases the cure rate of Helicobacter pylori infection when combined with rabeprazole, amoxicillin and clarithromycin. Isomoto H, Furusu H, Ohnita K, Wen CY, Inoue K, Kohno S.World J Gastroenterol. 2005 Mar 21;11(11):1629-33. PMID: 15786539 Free PMC Article</br>8:[Sofalcone]. Fukuda Y, Shimoyama T.Nihon Rinsho. 2002 Feb;60 Suppl 2:704-9. Review. Japanese. No abstract available. PMID: 11979875 </br>9:Inhibitory effect of sofalcone on tumor necrosis factor-alpha and interleukin-1 beta production in human monocytes stimulated by Helicobacter pylori water extract. Fujiwara Y, Higuchi K, Fukuda T, Watanabe T, Tominaga K, Arakawa T.Drugs Exp Clin Res. 2001;27(3):103-6. PMID: 11447767 </br>10:A novel in vitro effect of the mucosal protective agent sofalcone–inhibition of chemotactic motility in Helicobacter pylori. Yoshiyama H, Nakamura H, Okamoto T, Okita K, Nakazawa T.Aliment Pharmacol Ther. 2000 Apr;14 Suppl 1:230-6. PMID: 10807429 Free Article
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