Sodium gualenate

• CAT Number: I013035
• CAS Number: 6223-35-4
• Molecular Formula: C₁₅H₁₇NaO₃S
• Molecular Weight: 300.35
• Purity: ≥95%
• Target: Others
• Solubility: DMSO: 30 mg/mL
• IUPAC Name: sodium;3,8-dimethyl-5-propan-2-ylazulene-1-sulfonate
• InChI: InChI=1S/C15H18O3S.Na/c1-9(2)12-6-5-10(3)15-13(8-12)11(4)7-14(15)19(16,17)18;/h5-9H,1-4H3,(H,16,17,18);/q;+1/p-1
• InChIKey: GEYJUFBPCGDENK-UHFFFAOYSA-M
• SMILES: CC1=C2C(=CC(=C2C=C(C=C1)C(C)C)C)S(=O)(=O)[O-].[Na+]

Sodium gualenate (Guaiazulenesulfonate sodium) (Cat.No:I013035) is a hydrophilic derivative of guaiazulene with excellent anti-inflammatory and wound-healing effects mainly used for the treatment of duodenal ulcer, gastric ulcer and gastritis.

Reference

[1]. Nakamichi K, et al. Stabilization of sodium guaiazulene sulfonate in granules for tableting prepared using a twin-screw extruder. Eur J Pharm Biopharm. 2003 Nov;56(3):347-54.[2]. Cao T, et al. Synthesis and Biological Evaluation of 3, 8-dimethyl-5-isopropylazulene Derivatives as Anti-gastric Ulcer Agent. Chem Biol Drug Des. 2016 Aug;88(2):264-71.