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SMER18

SMER18

  • CAT Number: I005618
  • CAS Number: 944153-47-3
  • Molecular Formula: C16H14ClNO2
  • Molecular Weight: 287.74
  • Purity: ≥95%
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SMER18 (Cat No.:I005618) is a small molecule enhancer of Rapamycin, which acts as an mTOR-independent inducer of autophagy. If you need, please contact us in time, and we will reply as soon as possible within 24 hours.

Catalog Number I005618
CAS Number 944153-47-3
Molecular Formula

C16H14ClNO2

Purity 95%
Target mTOR
Solubility 10 mM in DMSO
Storage Store at -20°C
IUPAC Name (Z)-1-(4-chlorophenyl)-3-(3-hydroxyanilino)but-2-en-1-one
InChI InChI=1S/C16H14ClNO2/c1-11(18-14-3-2-4-15(19)10-14)9-16(20)12-5-7-13(17)8-6-12/h2-10,18-19H,1H3/b11-9-
InChIKey SNEQASFEVWLKOJ-LUAWRHEFSA-N
SMILES CC(=CC(=O)C1=CC=C(C=C1)Cl)NC2=CC(=CC=C2)O
Reference

[1]. Sarkar S, et al. Small molecules enhance autophagy and reduce toxicity in Huntington/’s disease models. Nat Chem Biol. 2007 Jun;3(6):331-338.

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