Sitafloxacin sesquihydrate is a broad-spectrum fluoroquinoline antibiotic that is particularly active against gram-positive bacteria such as a pneumococci.</br>Sitafloxacin has been shown to have a dual targeted mechanism of action. Other antibacterial quinolones target DNA gyrase or topoisomerase IV, but sitafloxacin targets both at a very similar rate. This double-target approach lowers the possibility of resistant strains.
| Catalog Number | A001015 |
| CAS Number | 163253-35-8 |
| Synonyms | DU-6859a |
| Molecular Formula | C19H18ClF2N3O3.3/2H2O |
| Purity | 95% |
| Storage | 3 years -20C powder |
| Reference | Onodera, Y., Uchida, Y., Tanaka, M., & Sato, K. (1999). Dual inhibitory activity of sitafloxacin (DU-6859a) against DNA gyrase and topoisomeraseIV of Streptococcus pneumoniae. Journal Of Antimicrobial Chemotherapy, 44(4), 533-536. http://dx.doi.org/10.1093/jac/44.4.533</span></p> |
