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Sinensetin

Sinensetin

  • CAT Number: I002758
  • CAS Number: 2306-27-6
  • Molecular Formula: C20H20O7
  • Molecular Weight: 372.4
  • Purity: ≥95%
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Sinensetin (Cat.No:I002758) is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin enhances adipogenesis and lipolysis. In vitro: Sinensetin promots adipogenesis in 3T3-L1 preadipocytes growing in incomplete differentiation medium, sinensetin enhances adipogenesis and lipolysis by increasing cAMP levels. 

Catalog Number I002758
CAS Number 2306-27-6
Molecular Formula

C20H20O7

Purity 95%
Solubility 10 mM in DMSO
Storage Store at -20°C
IUPAC Name 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxychromen-4-one
InChI InChI=1S/C20H20O7/c1-22-13-7-6-11(8-15(13)23-2)14-9-12(21)18-16(27-14)10-17(24-3)19(25-4)20(18)26-5/h6-10H,1-5H3
InChIKey LKMNXYDUQXAUCZ-UHFFFAOYSA-N
SMILES COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC)OC)OC)OC
Reference

<p style=/line-height:25px/>
<br>[1]. Kang SI et al. Sinensetin enhances adipogenesis and lipolysis by increasing cyclic adenosine monophosphate levels in 3T3-L1 adipocytes. Biol Pharm Bull. 2015;38(4):552-8.

<br>[2]. Shin HS et al. Sinensetin attenuates LPS-induced inflammation by regulating the protein level of IκB-α.
Biosci Biotechnol Biochem. 2012;76(4):847-9.

<br>[3]. Lam IK et al. In vitro and in vivo structure and activity relationship analysis of polymethoxylated flavonoids: identifying sinensetin as a novel antiangiogenesis agent. Mol Nutr Food Res. 2012 Jun;56(6):945-56.

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