For research use only. Not for therapeutic Use.
SID7970631（Cat No.:R024463）is a small-molecule inhibitor known for its ability to selectively target and inhibit protein phosphatase methylesterase-1 (PME-1), an enzyme that regulates the methylation status of protein phosphatase 2A (PP2A). By blocking PME-1 activity, SID7970631 enhances PP2A tumor suppressor function, restoring its phosphatase activity in cancer cells. This makes it a valuable tool in oncology research, particularly in studies focused on epigenetic regulation and phosphatase-mediated signaling. SID7970631 supports therapeutic exploration in cancers where PP2A activity is compromised and contributes to understanding PME-1’s role in tumor progression.
| CAS Number | 868224-75-3 |
| Synonyms | ethyl 2-[2-[2-(1,3-benzodioxol-5-ylmethylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxypropanoate |
| Molecular Formula | C24H24N2O7 |
| Purity | ≥95% |
| IUPAC Name | ethyl 2-[2-[2-(1,3-benzodioxol-5-ylmethylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxypropanoate |
| InChI | InChI=1S/C24H24N2O7/c1-3-30-24(29)15(2)33-19-6-4-5-18-17(19)9-10-26(23(18)28)13-22(27)25-12-16-7-8-20-21(11-16)32-14-31-20/h4-11,15H,3,12-14H2,1-2H3,(H,25,27) |
| InChIKey | NFBXJAYFPJYHPU-UHFFFAOYSA-N |
| SMILES | CCOC(=O)C(C)OC1=CC=CC2=C1C=CN(C2=O)CC(=O)NCC3=CC4=C(C=C3)OCO4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
