Schaftoside

• CAT Number: I018944
• CAS Number: 51938-32-0
• Molecular Formula: C₂₆H₂₈O₁₄
• Molecular Weight: 564.49
• Purity: ≥95%
• Storage: 2-8°C
• IUPAC Name: 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-8-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]chromen-4-one
• InChI: InChI=1S/C26H28O14/c27-6-13-18(32)21(35)23(37)26(40-13)15-19(33)14-10(29)5-12(8-1-3-9(28)4-2-8)39-24(14)16(20(15)34)25-22(36)17(31)11(30)7-38-25/h1-5,11,13,17-18,21-23,25-28,30-37H,6-7H2/t11-,13+,17-,18+,21-,22+,23+,25-,26-/m0/s1
• InChIKey: MMDUKUSNQNWVET-VYUBKLCTSA-N
• SMILES: C1C(C(C(C(O1)C2=C3C(=C(C(=C2O)C4C(C(C(C(O4)CO)O)O)O)O)C(=O)C=C(O3)C5=CC=C(C=C5)O)O)O)O

Schaftoside（Cat No.:I018944） is a flavonoid compound that is obtained from Desmodium radix. It serves as an important marker compound for assessing the quality of Desmodium radix. Schaftosides have been traditionally used in clinical settings for conditions like hepatitis, cholecystitis, gallstones, and urinary tract infections. Recent research has investigated the potential protective effects of schaftoside against non-alcoholic fatty liver disease (NAFLD) induced by a high-fat diet in mice.

Reference

[1]. Zhou K, et al. Schaftoside ameliorates oxygen glucose deprivation-induced inflammation associated with the TLR4/Myd88/Drp1-related mitochondrial fission in BV2 microglia cells. J Pharmacol Sci. 2019 Jan;139(1):15-22.