For research use only. Not for therapeutic Use.
SCH79797 dihydrochloride(CAT: M031092) is a synthetic small-molecule antagonist of the human protease-activated receptor-1 (PAR1), a G protein–coupled receptor involved in thrombin-mediated platelet activation, vascular tone, and inflammation. By selectively blocking PAR1 signaling, SCH79797 inhibits platelet aggregation and vascular smooth muscle cell responses, making it a valuable pharmacological tool for cardiovascular and thrombosis research. Beyond antithrombotic activity, studies have shown that SCH79797 exhibits antimicrobial and anticancer effects, partly through disrupting bacterial membranes and inducing tumor cell apoptosis. Its broad spectrum of biological actions highlights its utility in exploring PAR1-related pathways and in evaluating novel therapeutic approaches across multiple disease areas.
| CAS Number | 1216720-69-2 |
| Synonyms | 3-N-cyclopropyl-7-[(4-propan-2-ylphenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine;dihydrochloride |
| Molecular Formula | C23H27Cl2N5 |
| Purity | ≥95% |
| IUPAC Name | 3-N-cyclopropyl-7-[(4-propan-2-ylphenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine;dihydrochloride |
| InChI | InChI=1S/C23H25N5.2ClH/c1-14(2)16-5-3-15(4-6-16)13-28-12-11-18-20(28)10-9-19-21(18)22(24)27-23(26-19)25-17-7-8-17;;/h3-6,9-12,14,17H,7-8,13H2,1-2H3,(H3,24,25,26,27);2*1H |
| InChIKey | NNJTXSQXGHYXAJ-UHFFFAOYSA-N |
| SMILES | CC(C)C1=CC=C(C=C1)CN2C=CC3=C2C=CC4=C3C(=NC(=N4)NC5CC5)N.Cl.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
