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Cbz-NH-PEG3-CH2COOH

Cbz-NH-PEG3-CH2COOH

  • CAT Number: I016192
  • CAS Number: 462100-05-6
  • Molecular Formula: C₁₆H₂₃NO₇
  • Molecular Weight: 341.36
  • Purity: ≥95%
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Cbz-NH-PEG3-CH2COOH(CAT: I016192) is a valuable PEG-based linker essential for the synthesis of PROTAC molecules. This linker acts as a bridge between the target-binding ligand and the E3 ligase ligand within the PROTAC structure. The polyethylene glycol (PEG) moiety offers enhanced solubility, biocompatibility, and cellular permeability, facilitating effective intracellular delivery. The strategic incorporation of Cbz protecting group ensures controlled manipulation of the amino group, enabling precise conjugation in the synthesis process.

Catalog Number I016192
CAS Number 462100-05-6
Molecular Formula

C₁₆H₂₃NO₇

Purity 95%
Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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