SB 204070 hydrochloride

• CAT Number: I009304
• CAS Number: 148702-58-3
• Molecular Formula: C19H27ClN2O4
• Molecular Weight: 382.885
• Purity: ≥95%
• Synonyms: SB 204070 hydrochloride; SB 204070 HCl.;(1-butylpiperidin-4-yl)methyl 8-amino-7-chloro-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate
• Target: Beta-lactamase inhibitor
• Solubility: Soluble in DMSO
• Storage: Desiccate at RT
• IUPAC Name: (1-butylpiperidin-4-yl)methyl 5-amino-6-chloro-2,3-dihydro-1,4-benzodioxine-8-carboxylate
• InChI: InChI=1S/C19H27ClN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3
• InChIKey: AOOSJYIINXVNHV-UHFFFAOYSA-N
• SMILES: CCCCN1CCC(CC1)COC(=O)C2=CC(=C(C3=C2OCCO3)N)Cl

SB 204070 hydrochloride (Cat.No:I009304) is a novel beta-lactamase inhibitor isolated from Spondias mombin.

Reference

1:N-[(1-butyl-4-piperidinyl)methyl]-3,4dihydro-2H-[1,3]oxazino[3,2- a]indole10-carboxamide hydrochloride: the first potent and selective 5-HT4 receptor antagonist amide with oral activity. Gaster LM, Joiner GF, King FD, Wyman PA, Sutton JM, Bingham S, Ellis ES, Sanger GJ, Wardle KA.J Med Chem. 1995 Nov 24;38(24):4760-3. No abstract available. PMID: 7490724 2:(1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-1,4-benzodioxane-5-carboxylate hydrochloride: a highly potent and selective 5-HT4 receptor antagonist derived from metoclopramide. Gaster LM, Jennings AJ, Joiner GF, King FD, Mulholland KR, Rahman SK, Starr S, Wyman PA, Wardle KA, Ellis ES, et al.J Med Chem. 1993 Dec 10;36(25):4121-3. No abstract available. PMID: 8258837