For research use only. Not for therapeutic Use.
Saxagliptin hydrochloride（Cat No.:I014674）is an orally active antidiabetic agent that functions as a selective, reversible inhibitor of dipeptidyl peptidase-4 (DPP-4). By blocking DPP-4, it prevents the degradation of incretin hormones such as GLP-1 and GIP, thereby enhancing insulin secretion and reducing glucagon release in a glucose-dependent manner. This leads to improved glycemic control in patients with type 2 diabetes. The hydrochloride salt form enhances stability and handling. In research, saxagliptin hydrochloride is widely used to study incretin biology, glucose metabolism, and therapeutic strategies for diabetes and metabolic disorders.
| CAS Number | 709031-78-7 |
| Synonyms | (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile;hydrochloride |
| Molecular Formula | C18H26ClN3O2 |
| Purity | ≥95% |
| IUPAC Name | (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile;hydrochloride |
| InChI | InChI=1S/C18H25N3O2.ClH/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17;/h10-15,23H,1-7,9,20H2;1H/t10?,11?,12-,13+,14+,15-,17?,18?;/m1./s1 |
| InChIKey | TUAZNHHHYVBVBR-NHKADLRUSA-N |
| SMILES | C1[C@@H]2C[C@@H]2N([C@@H]1C#N)C(=O)[C@H](C34CC5CC(C3)CC(C5)(C4)O)N.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
