For research use only. Not for therapeutic Use.
Sarizotan（Cat No.:I015404）is a selective serotonin 5-HT1A receptor agonist and dopamine D2-like receptor antagonist, developed for neurological and psychiatric research. Its dual activity modulates serotonergic and dopaminergic pathways, offering potential benefits in treating movement disorders, mood regulation, and neurodegeneration. Sarizotan has been investigated in clinical studies for Rett syndrome, Parkinson’s disease, and related conditions, where it demonstrated efficacy in reducing breathing irregularities and motor complications. With its unique receptor profile, Sarizotan serves as a valuable pharmacological tool for exploring serotonin–dopamine interactions and advancing therapeutic strategies in neuroscience research.
| CAS Number | 351862-32-3 |
| Synonyms | 1-[(2R)-3,4-dihydro-2H-chromen-2-yl]-N-[[5-(4-fluorophenyl)pyridin-3-yl]methyl]methanamine |
| Molecular Formula | C22H21FN2O |
| Purity | ≥95% |
| IUPAC Name | 1-[(2R)-3,4-dihydro-2H-chromen-2-yl]-N-[[5-(4-fluorophenyl)pyridin-3-yl]methyl]methanamine |
| InChI | InChI=1S/C22H21FN2O/c23-20-8-5-17(6-9-20)19-11-16(12-24-14-19)13-25-15-21-10-7-18-3-1-2-4-22(18)26-21/h1-6,8-9,11-12,14,21,25H,7,10,13,15H2/t21-/m1/s1 |
| InChIKey | HKFMQJUJWSFOLY-OAQYLSRUSA-N |
| SMILES | C1CC2=CC=CC=C2O[C@H]1CNCC3=CC(=CN=C3)C4=CC=C(C=C4)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
