GSK840 - CAS 2361146-30-5

GSK840 (Cat No.:I019282) is a potent inhibitor of receptor-interacting protein kinase 3 (RIP3 or RIPK3). It binds to the kinase domain of RIP3 with high affinity, exhibiting an IC50 of 0.9 nM. Additionally, GSK840 effectively inhibits the kinase activity of RIP3, with an IC50 value of 0.3 nM. By targeting RIP3, this compound holds the potential for modulating cell death pathways and has implications in various disease contexts, including inflammatory and immune-related disorders.

Catalog Number: I019282

CAS Number: 2361146-30-5

Molecular Formula: C₂₁H₂₃N₃O₃

Molecular Weight:365.43

Purity: ≥95%

* For research use only. Not for human or veterinary use.


Molecular Formula: C₂₁H₂₃N₃O₃
Molecular Weight365.43
StorageStore at -20°C

Computed Descriptor

IUPAC Nametert-butyl 2-[4-[5-(methylcarbamoyl)benzimidazol-1-yl]phenyl]acetate