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sAJM589

sAJM589

  • CAT Number: I018145
  • CAS Number: 2089-82-9
  • Molecular Formula: C₁₆H₁₀N₂O
  • Molecular Weight: 246.26
  • Purity: ≥95%
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sAJM589（Cat No.:I018145） is a potent Myc inhibitor that disrupts the formation of Myc-Max heterodimers. It exhibits an inhibitory concentration (IC50) of 1.8 μM. By preventing the association of Myc with Max, sAJM589 interferes with the transcriptional activity of the Myc protein, which is involved in cell growth and proliferation. The inhibition of Myc-Max heterodimerization by sAJM589 represents a potential therapeutic strategy for targeting Myc-driven cancers and other diseases associated with dysregulated Myc signaling.

Catalog Number I018145
CAS Number 2089-82-9
Molecular Formula

C₁₆H₁₀N₂O

Purity 95%
Storage Store at -20°C
IUPAC Name benzo[a]phenazin-5-ol
InChI InChI=1S/C16H10N2O/c19-15-9-14-16(11-6-2-1-5-10(11)15)18-13-8-4-3-7-12(13)17-14/h1-9,19H
InChIKey WZBDRAAGHRCRKM-UHFFFAOYSA-N
SMILES C1=CC=C2C(=C1)C(=CC3=NC4=CC=CC=C4N=C23)O
Reference

[1]. Choi SH, et al. Targeted Disruption of Myc-Max Oncoprotein Complex by a Small Molecule. ACS Chem Biol. 2017 Nov 17;12(11):2715-2719.

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