S-acetyl-PEG2-Boc

• CAT Number: I016484
• CAS Number: 1820641-93-7
• Molecular Formula: C13H24O5S
• Molecular Weight: 292.39
• Purity: ≥95%
• Synonyms: tert-butyl 3-[2-(2-acetylsulfanylethoxy)ethoxy]propanoate
• InChI: InChI=1S/C13H24O5S/c1-11(14)19-10-9-17-8-7-16-6-5-12(15)18-13(2,3)4/h5-10H2,1-4H3
• InChIKey: DSBKYHJZFUGMFX-UHFFFAOYSA-N
• SMILES: CC(=O)SCCOCCOCCC(=O)OC(C)(C)C

S-acetyl-PEG2-Boc(CAT: I016484) is a protected heterobifunctional PEG linker featuring an S-acetyl-protected thiol on one end and a Boc-protected amine on the other. The PEG2 spacer provides short hydrophilic flexibility, enhancing solubility and reducing steric hindrance in conjugation reactions. Upon deprotection, the thiol group can participate in selective coupling with maleimides or other thiol-reactive groups, while the Boc-protected amine can be revealed to enable amide bond formation with carboxylic acids or activated esters. This dual functionality makes S-acetyl-PEG2-Boc a valuable tool in bioconjugation, linker design, and the preparation of multifunctional molecules for drug development and chemical biology research.