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PS 48

PS 48

  • CAT Number: I011730
  • CAS Number: 1180676-32-7
  • Molecular Formula: C17H15ClO2
  • Molecular Weight: 286.755
  • Purity: ≥95%
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PS48(CAT: I011730) is a potent and selective sphingosine kinase 1 (SphK1) inhibitor. It inhibits SphK1 activity by binding to its ATP pocket. SphK1 is an enzyme involved in the regulation of cell proliferation, differentiation, migration, and apoptosis. Inhibition of SphK1 has been shown to have therapeutic potential in various diseases, including cancer, inflammation, and fibrosis. PS48 has been studied as a potential therapeutic agent for cancer treatment.

Catalog Number I011730
CAS Number 1180676-32-7
Molecular Formula

C17H15ClO2

Purity 95%
Target PDK-1
Solubility Soluble in DMSO > 10 mM
Storage Store at +4C
IUPAC Name (Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid
InChI InChI=1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12-
InChIKey LLJYFDRQFPQGNY-QINSGFPZSA-N
SMILES C1=CC=C(C=C1)C(=CC(=O)O)CCC2=CC=C(C=C2)Cl

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