Rupatadine

  • CAT Number: I002017
  • CAS Number: 158876-82-5
  • Molecular Formula: C26H26ClN3
  • Molecular Weight: 415.96
  • Purity: ≥95%
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Rupatadine (Cat.No:I002017) is an antihistamine medication used to relieve allergy symptoms, such as itching and sneezing. It selectively blocks histamine H1 receptors and exhibits additional anti-inflammatory properties. Rupatadine is commonly prescribed for the treatment of allergic rhinitis and chronic idiopathic urticaria, providing effective and long-lasting symptom relief.

Catalog Number I002017
CAS Number 158876-82-5
Molecular Formula

C26H26ClN3

Purity 95%
Target PAF/H1 antagonist
Solubility 10 mM in DMSO
Storage Store at -20°C
Reference

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<br>[1]. Merlos M, et al. Rupatadine, a new potent, orally active dual antagonist of histamine and platelet-activating factor (PAF). J Pharmacol Exp Ther. 1997 Jan;280(1):114-21.
<br>[2]. Queralt M, et al. In vitro inhibitory effect of rupatadine on histamine and TNF-alpha release from dispersed canine skin mast cells and the human mast cell line HMC-1. Inflamm Res. 2000 Jul;49(7):355-60.
<br>[3]. Lv XX, et al. Rupatadine protects against pulmonary fibrosis by attenuating PAF-mediated senescence in rodents. PLoS One. 2013 Jul 15;8(7):e68631.
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