RSV-IN-1

• CAT Number: I019818
• CAS Number: 861139-16-4
• Molecular Formula: C₂₀H₂₁N₅O₄S
• Molecular Weight: 427.48
• Purity: ≥95%
• Storage: Store at -20°C
• IUPAC Name: N-(2-hydroxyethyl)-4-methoxy-N-methyl-3-(6-methyl-[1,2,4]triazolo[3,4-a]phthalazin-3-yl)benzenesulfonamide
• InChI: InChI=1S/C20H21N5O4S/c1-13-15-6-4-5-7-16(15)19-21-22-20(25(19)23-13)17-12-14(8-9-18(17)29-3)30(27,28)24(2)10-11-26/h4-9,12,26H,10-11H2,1-3H3
• InChIKey: RKHSOIYWKCMPHF-UHFFFAOYSA-N
• SMILES: CC1=NN2C(=NN=C2C3=C(C=CC(=C3)S(=O)(=O)N(C)CCO)OC)C4=CC=CC=C14

RSV-IN-1（Cat No.:I019818） is a small molecule inhibitor that specifically targets human respiratory syncytial virus (RSV), a major cause of respiratory infections. It has an IC50 value of 0.11 μM, indicating potent antiviral activity against hRSV. RSV-IN-1 has been shown to act by targeting the viral fusion protein, which is essential for viral entry into host cells. This mechanism of action suggests that RSV-IN-1 may have the potential as a therapeutic agent for the treatment of hRSV infections.

Reference

[1]. Lundin A, et al. Two novel fusion inhibitors of human respiratory syncytial virus. Antiviral Res. 2010 Dec;88(3):317-24.