For research use only. Not for therapeutic Use.
(RS)-PPG（Cat No.:M028563）, also known as (RS)-propargylglycine, is an irreversible inhibitor of cystathionine γ-lyase (CSE), a key enzyme in the transsulfuration pathway responsible for generating hydrogen sulfide (H₂S). By blocking CSE activity, (RS)-PPG reduces endogenous H₂S production, making it a widely used tool in biochemical and pharmacological studies. Researchers employ it to investigate the physiological and pathological roles of H₂S in cardiovascular function, inflammation, and neurological regulation. (RS)-PPG is valuable in exploring redox biology, sulfur metabolism, and therapeutic strategies targeting gasotransmitter signaling pathways.
| CAS Number | 120667-15-4 |
| Synonyms | 2-amino-2-(4-phosphonophenyl)acetic acid |
| Molecular Formula | C8H10NO5P |
| Purity | ≥95% |
| IUPAC Name | 2-amino-2-(4-phosphonophenyl)acetic acid |
| InChI | InChI=1S/C8H10NO5P/c9-7(8(10)11)5-1-3-6(4-2-5)15(12,13)14/h1-4,7H,9H2,(H,10,11)(H2,12,13,14) |
| InChIKey | JRQRKFDFHAPMGQ-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1C(C(=O)O)N)P(=O)(O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
