Rosmarinic acid

• CAT Number: I002562
• CAS Number: 20283-92-5
• Molecular Formula: C18H16O8
• Molecular Weight: 360.3
• Purity: ≥95%
• Solubility: DMSO: ≥ 32 mg/mL
• Storage: 2-8°C
• IUPAC Name: (2R)-3-(3,4-dihydroxyphenyl)-2-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxypropanoic acid
• InChI: InChI=1S/C18H16O8/c19-12-4-1-10(7-14(12)21)3-6-17(23)26-16(18(24)25)9-11-2-5-13(20)15(22)8-11/h1-8,16,19-22H,9H2,(H,24,25)/b6-3+/t16-/m1/s1
• InChIKey: DOUMFZQKYFQNTF-WUTVXBCWSA-N
• SMILES: C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O

Rosmarinic acid（Cat No.:I002562） is a naturally-occurring polyphenol known for its antioxidative and anti-inflammatory properties. It exhibits potent antioxidant effects, found in various herbs, such as rosemary and basil, protecting against oxidative stress-induced damage. Additionally, rosmarinic acid demonstrates anti-inflammatory activity by inhibiting inflammatory mediators and enzymes. Its natural origin, along with its antioxidative and anti-inflammatory properties, positions rosmarinic acid as a promising compound for potential therapeutic applications in various diseases and as a dietary supplement for overall health and well-being.

Reference

[1]. Chiaki Sanbongi, et al. Rosmarinic acid inhibits lung injury induced by diesel exhaust particles. Free Radical Biology and Medicine Volume 34, Issue 8, 15 April 2003, Pages 1060–1069
[2]. Hiroshi Takeda, et al. Rosmarinic acid and caffeic acid produce antidepressive-like effect in the forced swimming test in mice. European Journal of Pharmacology Volume 449, Issue 3, 9 August 2002, Pages 261–267
[3]. Pereira P, et al. Neurobehavioral and genotoxic aspects of rosmarinic acid. Pharmacol Res. 2005 Sep;52(3):199-203.
[4]. Wenqing Xu, et al. Protective effects of rosmarinic acid against radiation-induced damage to the hematopoietic system in mice. J Radiat Res. 2016 Mar 22. pii: rrw021
[5]. Fernando PM, et al. Rosmarinic Acid Attenuates Cell Damage against UVB Radiation-Induced Oxidative Stress via Enhancing Antioxidant Effects in Human HaCaT Cells. Biomol Ther (Seoul). 2016 Jan;24(1):75-84.