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Ro 10-5824 dihydrochloride

Ro 10-5824 dihydrochloride

  • CAT Number: I010540
  • CAS Number: 189744-94-3
  • Molecular Formula: C17H22Cl2N4
  • Molecular Weight: 353.291
  • Purity: ≥95%
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Ro 10-5824 dihydrochloride (Cat.No:I010540) is a chemical compound that acts as a selective positive allosteric modulator of the α7 nicotinic acetylcholine receptor (nAChR). It has shown potential in preclinical studies for its cognitive-enhancing effects and neuroprotective properties. Ro 10-5824 dihydrochloride may have therapeutic applications in neurodegenerative disorders like Alzheimer’s disease.

Catalog Number I010540
CAS Number 189744-94-3
Molecular Formula

C17H22Cl2N4

Purity 95%
Target Dopamine Receptor
Solubility Soluble to 100 mM in water and to 75 mM in DMSO
Storage Desiccate at RT
IUPAC Name 2-methyl-5-[(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methyl]pyrimidin-4-amine;dihydrochloride
InChI InChI=1S/C17H20N4.2ClH/c1-13-19-11-16(17(18)20-13)12-21-9-7-15(8-10-21)14-5-3-2-4-6-14;;/h2-7,11H,8-10,12H2,1H3,(H2,18,19,20);2*1H
InChIKey UZHMRJRDYCRKIZ-UHFFFAOYSA-N
SMILES CC1=NC=C(C(=N1)N)CN2CCC(=CC2)C3=CC=CC=C3.Cl.Cl

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