Rigin

For research use only. Not for therapeutic Use.

  • CAT Number: I035577
  • CAS Number: 77727-17-4
  • Molecular Formula: C18H32N8O6
  • Molecular Weight: 456.5
  • Purity: 98%
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Rigin is a Tuftsin-like tetrapeptide with equal phagocytosis stimulating activity.


Catalog Number I035577
CAS Number 77727-17-4
Synonyms

Gly-gln-pro-arg; GQPR; Rigin; Tetrapeptide-3; Tetrapeptide-7

Molecular Formula C18H32N8O6
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name L-Arginine, N2-(1-(N2-glycyl-L-glutaminyl)-L-prolyl)-
InChI InChI=1S/C18H32N8O6/c19-9-14(28)24-10(5-6-13(20)27)16(30)26-8-2-4-12(26)15(29)25-11(17(31)32)3-1-7-23-18(21)22/h10-12H,1-9,19H2,(H2,20,27)(H,24,28)(H,25,29)(H,31,32)(H4,21,22,23)/t10-,11-,12-/m0/s1
InChIKey UEJYSALTSUZXFV-SRVKXCTJSA-N
SMILES NCC(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)O
Reference

1. Dutta RC, Puri A, Anand N. Immunomodulatory potential of hydrophobic analogs of Rigin and their role in providing protection against Plasmodium berghei infection in mice. Int Immunopharmacol. 2001 May;1(5):843-55. doi: 10.1016/s1567-5769(01)00021-2. PMID: 11379040.
2. Veretennikova NI, Chipens GI, Nikiforovich GV, Betinsh YR. Rigin, another phagocytosis-stimulating tetrapeptide isolated from human IgG. Confirmations of a hypothesis. Int J Pept Protein Res. 1981 Apr;17(4):430-5. doi: 10.1111/j.1399-3011.1981.tb02011.x. PMID: 7309346.

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