Cinobufotalin

• CAT Number: I000438
• CAS Number: 1108-68-5
• Molecular Formula: C26H34O7
• Molecular Weight: 458.54
• Purity: ≥95%
• Solubility: DMSO: 35 mg/mL
• Storage: Store at -20C

Cinobufotalin(CAS: I000438) is a natural compound derived from toad venom belonging to the class of bufadienolides. It exhibits anticancer activity and has been studied for its potential therapeutic applications in cancer treatment. Bufadienolides are known to exert cytotoxic effects by inhibiting cell proliferation, inducing apoptosis, and disrupting various cellular processes involved in cancer progression. However, it is important to note that the use of cinobufotalin or any other natural compounds for cancer treatment requires further research and evaluation to determine its efficacy, safety, and optimal dosage.

Reference

[1]. Emam H, et al. Apoptotic cell death by the novel natural compound, cinobufotalin. Chem Biol Interact. 2012 Sep 30;199(3):154-60.

[2]. Kai S, et al. Pre-clinical evaluation of cinobufotalin as a potential anti-lung cancer agent. Biochem Biophys Res Commun. 2014 Sep 26;452(3):768-74.

[3]. Cheng L, et al. Ceramide production mediates cinobufotalin-induced growth inhibition and apoptosis in cultured hepatocellular carcinoma cells. Tumour Biol. 2015 Feb 28.