RGLS4326

• CAT Number: I044428
• CAS Number: 2229964-07-0
• Molecular Formula: C95H115F3N32O51P8S8
• Molecular Weight: 3082.42
• Purity: ≥95%

RGLS4326（Cat No.:I044428）is an antisense oligonucleotide specifically designed to inhibit microRNA-17 (miR-17), a key regulator of gene networks involved in kidney development and function. By selectively binding to and blocking miR-17, RGLS4326 restores the expression of downstream targets that are suppressed in diseases like autosomal dominant polycystic kidney disease (ADPKD). It has demonstrated efficacy in preclinical models by reducing cyst growth and improving kidney function. RGLS4326 represents a promising therapeutic candidate for RNA-targeted treatment of genetic kidney disorders, offering a novel approach to modulating pathogenic microRNA activity in vivo.