Resveratrol

• CAT Number: A000646
• CAS Number: 501-36-0
• Molecular Formula: C14H12O3
• Molecular Weight: 228.24
• Purity: ≥95%
• Synonyms: trans-resveratrol; 3,4′,5-Trihydroxystilbene
• Target: Autophagy
• Solubility: >9.7mg/mL in DMSO
• Storage: <label class=
• IUPAC Name: 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol
• InChI: InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+
• InChIKey: LUKBXSAWLPMMSZ-OWOJBTEDSA-N
• SMILES: C1=CC(=CC=C1C=CC2=CC(=CC(=C2)O)O)O

Resveratrol (Cat No.: A000646) is a natural polyphenol found in grapes, red wine, berries, and peanuts, known for its antioxidant and anti-inflammatory properties. It is studied for potential health benefits, including cardiovascular protection, anti-aging effects, and cancer prevention. Resveratrol may work by activating sirtuins and modulating cellular signaling pathways involved in oxidative stress and inflammation. Often used as a dietary supplement, it is generally well-tolerated, though its bioavailability is low. Research continues into its role in metabolic, neurodegenerative, and age-related diseases.

Overview of Clinical Research

Resveratrol is an antioxidant and a ribonucleotide reductase inhibitor as well as a SIRT1 protein stimulant. It has been granted for its orphan drug status in MELAS syndrome.

Reference

1: Granados-Soto V. Pleiotropic effects of resveratrol. Drug News Perspect. 2003 Jun;16(5):299-307. Review. PubMed PMID: 12942161.
2: Kimura Y. Pharmacological studies on resveratrol. Methods Find Exp Clin Pharmacol. 2003 May;25(4):297-310. Review. PubMed PMID: 12808475.
3: Ratan HL, Steward WP, Gescher AJ, Mellon JK. Resveratrol–a prostate cancer chemopreventive agent? Urol Oncol. 2002 Nov-Dec;7(6):223-7. Review. PubMed PMID: 12504842.
4: Ignatowicz E, Baer-Dubowska W. Resveratrol, a natural chemopreventive agent against degenerative diseases. Pol J Pharmacol. 2001 Nov-Dec;53(6):557-69. Review. PubMed PMID: 11985329.