Ramipril - CAS 87333-19-5

Ramipril (Cat No.:A000717) is an antihypertensive agent, an angiotensin-converting enzyme (ACE) inhibitor that converts to an active diacid metabolite. It is used for renal and mild, moderate and severe essential hypertension, as well as moderate and malignant congestive heart failure.

Catalog Number: A000717

CAS Number: 87333-19-5

PubChem Substance ID:355038785

Molecular Formula: C23H32N2O5

Molecular Weight:416.5

Purity: ≥95%

Inventory:In Stock

* For research use only. Not for human or veterinary use.


Property

Molecular Formula: C23H32N2O5
Molecular Weight416.5
Target:ACE
Solubility>17.6mg/mL in DMSO
Purity≥95%
Storage<label class=
Overview of Clinical Research<span style=”color:#000000;”><span style=”font-family:arial,helvetica,sans-serif;”><span style=”font-size:12px;”>Ramipril is an ACE inhibitor. The&nbsp;<span style=”orphans: 2; widows: 2;”>Phase-II clinical trials in COVID-2019 infections starts in USA (PO) (NCT04366050).</span></span></span></span>

Computed Descriptor

IUPAC Name(2S,3aS,6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid
InChIInChI=1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1
InChIKeyHDACQVRGBOVJII-JBDAPHQKSA-N
SMILESO=C([C@H](C)N[C@H](C(OCC)=O)CCC1=CC=CC=C1)N2[C@]3([H])[C@](CCC3)([H])C[C@H]2C(O)=O