rac Perhexiline Maleate

• CAT Number: R046297
• CAS Number: 6724-53-4
• Molecular Formula: C19H35N • C4H4O4
• Molecular Weight: 393.6
• Purity: ≥95%
• Target: CPT1
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: (Z)-but-2-enedioic acid;2-(2,2-dicyclohexylethyl)piperidine
• InChI: InChI=1S/C19H35N.C4H4O4/c1-3-9-16(10-4-1)19(17-11-5-2-6-12-17)15-18-13-7-8-14-20-18;5-3(6)1-2-4(7)8/h16-20H,1-15H2;1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChIKey: JDZOTSLZMQDFLG-BTJKTKAUSA-N
• SMILES: C1CCC(CC1)C(CC2CCCCN2)C3CCCCC3.C(=CC(=O)O)C(=O)O

Perhexiline maleate (CAS 6724-53-4) is an anti-anginal metabolic modulator. It inhibits the mitochondrial enzyme carnitine palmitoyltransferase CPT-1 and to a lesser extent CPT-2. This causes a shift in myocardial substrate utilisation from long chain fatty acids to carbohydrates, resulting in increased glucose and lactate utilization and increased ATP production for the same O2 consumption as before and consequently increases myocardial efficiency.

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