R-(-)-Clopidogrel Hydrogen Sulfate

• CAT Number: R012382
• CAS Number: 120202-71-3
• Molecular Formula: C16H18ClNO6S2
• Molecular Weight: 419.89
• Purity: ≥95%
• Synonyms: (R)-(-)-Methyl 2-(2-Chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate Hydrogen Sulfate; (R)-Clopidogrel Bisulfate; SR 25989C
• Storage: -20°C
• IUPAC Name: methyl (2R)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate;sulfuric acid
• InChI: InChI=1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)/t15-;/m1./s1
• InChIKey: FDEODCTUSIWGLK-XFULWGLBSA-N
• SMILES: COC(=O)[C@@H](C1=CC=CC=C1Cl)N2CCC3=C(C2)C=CS3.OS(=O)(=O)O

R-(–)-Clopidogrel hydrogen sulfate（Cat No.:R012382）is the enantiomer of the active pharmaceutical ingredient clopidogrel, a thienopyridine-class antiplatelet agent. As the R-enantiomer, it is considered the inactive form compared to the therapeutically active S-(+)-clopidogrel. It contains a chiral center, a thieno[3,2-c]pyridine core, and a methyl ester functional group, formulated as a hydrogen sulfate salt to enhance solubility and stability. Though pharmacologically inactive, the R-enantiomer is important in chiral purity analysis and regulatory control during drug synthesis. It plays a critical role in quality assurance and enantiomeric resolution in pharmaceutical manufacturing.