For research use only. Not for therapeutic Use.
(R)-BDP9066（Cat No.:I044133）is a potent and selective inhibitor of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MK2), a downstream effector of the p38 MAPK signaling pathway involved in inflammation, stress response, and cancer progression. The (R)-enantiomer offers enhanced selectivity and efficacy, making it an ideal tool for dissecting MK2-specific biological functions. (R)-BDP9066 is used in preclinical studies to evaluate anti-inflammatory strategies and investigate the role of MK2 in tumor growth, cytokine production, and cellular stress response. It supports therapeutic development in inflammatory diseases and oncology research.
| CAS Number | 2284549-25-1 |
| Synonyms | (6R)-8-(3-pyrimidin-4-yl-1H-pyrrolo[2,3-b]pyridin-4-yl)-1,8-diazaspiro[5.5]undecane |
| Molecular Formula | C20H24N6 |
| Purity | ≥95% |
| IUPAC Name | (6R)-8-(3-pyrimidin-4-yl-1H-pyrrolo[2,3-b]pyridin-4-yl)-1,8-diazaspiro[5.5]undecane |
| InChI | InChI=1S/C20H24N6/c1-2-8-25-20(6-1)7-3-11-26(13-20)17-5-10-22-19-18(17)15(12-23-19)16-4-9-21-14-24-16/h4-5,9-10,12,14,25H,1-3,6-8,11,13H2,(H,22,23)/t20-/m1/s1 |
| InChIKey | UELSMLDRSQFVHG-HXUWFJFHSA-N |
| SMILES | C1CCN[C@]2(C1)CCCN(C2)C3=C4C(=CNC4=NC=C3)C5=NC=NC=C5 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
