Quercetin

  • CAT Number: I011999
  • CAS Number: 17-39-5
  • Molecular Formula: C15H10O7
  • Molecular Weight: 302.238
  • Purity: ≥95%
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Quercetin is a plant polyphenol from the flavonoid group, found in many fruits, vegetables, leaves, and grains. It can be used as an ingredient in supplements, beverages, or foods. Quercetin has been reported to inhibit the oxidation of other molecules and hence is classified as an antioxidant. Quercetin contains a polyphenolic chemical substructure that stops oxidation by acting as a scavenger of free radicals that are responsible for oxidative chain reactions. Quercetin also activates or inhibits the activities of a number of proteins.

Catalog Number I011999
CAS Number 17-39-5
Molecular Formula

C15H10O7

Purity 95%
Solubility Soluble in DMSO
Storage Store at 0-8 °C
InChI InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H
InChIKey REFJWTPEDVJJIY-UHFFFAOYSA-N
SMILES O=C1C(O)=C(C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C13
Reference

</br>1: Massi A, Bortolini O, Ragno D, Bernardi T, Sacchetti G, Tacchini M, De Risi C. Research Progress in the Modification of Quercetin Leading to Anticancer Agents. Molecules. 2017 Jul 29;22(8). pii: E1270. doi: 10.3390/molecules22081270. Review. PubMed PMID: 28758919.</br>2: Marunaka Y. Actions of quercetin, a flavonoid, on ion transporters: its physiological roles. Ann N Y Acad Sci. 2017 Jun;1398(1):142-151. doi: 10.1111/nyas.13361. Epub 2017 Jun 2. Review. PubMed PMID: 28574574.</br>3: Mohammadi-Sartang M, Mazloom Z, Sherafatmanesh S, Ghorbani M, Firoozi D. Effects of supplementation with quercetin on plasma C-reactive protein concentrations: a systematic review and meta-analysis of randomized controlled trials. Eur J Clin Nutr. 2017 May 24. doi: 10.1038/ejcn.2017.55. [Epub ahead of print] Review. PubMed PMID: 28537580.</br>4: Terao J. Factors modulating bioavailability of quercetin-related flavonoids and the consequences of their vascular function. 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Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid. Pharmacogn Rev. 2016 Jul-Dec;10(20):84-89. doi: 10.4103/0973-7847.194044. Review. PubMed PMID: 28082789; PubMed Central PMCID: PMC5214562.</br>9: McKay TB, Karamichos D. Quercetin and the ocular surface: What we know and where we are going. Exp Biol Med (Maywood). 2017 Mar;242(6):565-572. doi: 10.1177/1535370216685187. Epub 2017 Jan 5. Review. PubMed PMID: 28056553.</br>10: Chen S, Jiang H, Wu X, Fang J. Therapeutic Effects of Quercetin on Inflammation, Obesity, and Type 2 Diabetes. Mediators Inflamm. 2016;2016:9340637. doi: 10.1155/2016/9340637. Epub 2016 Nov 28. Review. PubMed PMID: 28003714; PubMed Central PMCID: PMC5149671.</br>11: Parvaresh A, Razavi R, Rafie N, Ghiasvand R, Pourmasoumi M, Miraghajani M. Quercetin and ovarian cancer: An evaluation based on a systematic review. J Res Med Sci. 2016 May 9;21:34. eCollection 2016. Review. PubMed PMID: 27904580; PubMed Central PMCID: PMC5122222.</br>12: Harris Z, Donovan MG, Branco GM, Limesand KH, Burd R. Quercetin as an Emerging Anti-Melanoma Agent: A Four-Focus Area Therapeutic Development Strategy. Front Nutr. 2016 Oct 31;3:48. eCollection 2016. Review. PubMed PMID: 27843913; PubMed Central PMCID: PMC5086580.</br>13: Oboh G, Ademosun AO, Ogunsuyi OB. Quercetin and Its Role in Chronic Diseases. Adv Exp Med Biol. 2016;929:377-387. Review. PubMed PMID: 27771934.</br>14: Suganthy N, Devi KP, Nabavi SF, Braidy N, Nabavi SM. Bioactive effects of quercetin in the central nervous system: Focusing on the mechanisms of actions. Biomed Pharmacother. 2016 Dec;84:892-908. doi: 10.1016/j.biopha.2016.10.011. Epub 2016 Oct 15. Review. PubMed PMID: 27756054.</br>15: Eid HM, Haddad PS. The Antidiabetic Potential of Quercetin: Underlying Mechanisms. Curr Med Chem. 2017;24(4):355-364. doi: 10.2174/0929867323666160909153707. Review. PubMed PMID: 27633685.</br>16: Khan F, Niaz K, Maqbool F, Ismail Hassan F, Abdollahi M, Nagulapalli Venkata KC, Nabavi SM, Bishayee A. Molecular Targets Underlying the Anticancer Effects of Quercetin: An Update. Nutrients. 2016 Aug 29;8(9). pii: E529. doi: 10.3390/nu8090529. Review. PubMed PMID: 27589790; PubMed Central PMCID: PMC5037516.</br>17: Hatahet T, Morille M, Hommoss A, Devoisselle JM, Müller RH, Bégu S. Quercetin topical application, from conventional dosage forms to nanodosage forms. Eur J Pharm Biopharm. 2016 Nov;108:41-53. doi: 10.1016/j.ejpb.2016.08.011. Epub 2016 Aug 24. Review. PubMed PMID: 27565033.</br>18: Kashyap D, Mittal S, Sak K, Singhal P, Tuli HS. Molecular mechanisms of action of quercetin in cancer: recent advances. Tumour Biol. 2016 Oct;37(10):12927-12939. Epub 2016 Jul 22. Review. PubMed PMID: 27448306.</br>19: Mlcek J, Jurikova T, Skrovankova S, Sochor J. Quercetin and Its Anti-Allergic Immune Response. 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