PU 23

• CAT Number: I035200
• CAS Number: 817635-93-1
• Molecular Formula: C21H19N3O3S2
• Molecular Weight: 425.52
• Purity: ≥95%
• Synonyms: N-[[4-(benzylsulfamoyl)phenyl]carbamothioyl]benzamide
• InChI: InChI=1S/C21H19N3O3S2/c25-20(17-9-5-2-6-10-17)24-21(28)23-18-11-13-19(14-12-18)29(26,27)22-15-16-7-3-1-4-8-16/h1-14,22H,15H2,(H2,23,24,25,28)
• InChIKey: RYIRRFWVFHEXTH-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)CNS(=O)(=O)C2=CC=C(C=C2)NC(=S)NC(=O)C3=CC=CC=C3

PU 23（Cat No.:I035200）is a small-molecule inhibitor targeting the heat shock protein 90 (Hsp90), a molecular chaperone involved in stabilizing and activating numerous client proteins critical for cancer cell growth and survival. By disrupting Hsp90 function, PU 23 promotes the degradation of oncogenic proteins, leading to cell cycle arrest and apoptosis in tumor cells. It is part of the purine-scaffold class of Hsp90 inhibitors, offering specificity and potency in preclinical models. PU 23 is primarily used in cancer research to study Hsp90-dependent pathways and explore therapeutic strategies targeting protein homeostasis.