Dimethandrolone Undecanoate

• CAT Number: I006388
• CAS Number: 366472-45-9
• Molecular Formula: C31H50O3
• Molecular Weight: 470.738
• Purity: ≥95%
• Target: Selective Androgen Receptor Modulator
• Solubility: Soluble in DMSO
• Storage: 0 - 4°C for short term or -20 °C for long term
• InChI: InChI=1S/C31H50O3/c1-5-6-7-8-9-10-11-12-13-28(33)34-27-17-16-26-30-21(2)18-23-19-24(32)14-15-25(23)29(30)22(3)20-31(26,27)4/h19,21-22,25-27,29-30H,5-18,20H2,1-4H3/t21-,22+,25+,26+,27+,29-,30+,31+/m1/s1
• InChIKey: FVICENFBEMJOCE-RTFNQGFNSA-N
• SMILES: C[C@@]12[C@@H](OC(CCCCCCCCCC)=O)CC[C@@]1([H])[C@]3([H])[C@H](C)CC4=CC(CC[C@]4([H])[C@@]3([H])[C@@H](C)C2)=O

Dimethandrolone Undecanoate, also known as DMAU, is a selective androgen receptor modulator (SARM) potentially for the treatment of male contraception. Dimethandrolone Undecanoate has both androgenic and progestational activities, properties that may maximize gonadotropin suppression. The dual androgenic and progestational activities of DMA make it a potential candidate for a single-agent male contraceptive as well as for androgen therapy in men.

Reference

1:Comparison of the single dose pharmacokinetics, pharmacodynamics, and safety of two novel oral formulations of dimethandrolone undecanoate (DMAU): a potential oral, male contraceptive. Ayoub R, Page ST, Swerdloff RS, Liu PY, Amory JK, Leung A, Hull L, Blithe D, Christy A, Chao JH, Bremner WJ, Wang C.Andrology. 2017 Mar;5(2):278-285. doi: 10.1111/andr.12303. Epub 2016 Dec 1. PMID: 27907978 2:Single, escalating dose pharmacokinetics, safety and food effects of a new oral androgen dimethandrolone undecanoate in man: a prototype oral male hormonal contraceptive. Surampudi P, Page ST, Swerdloff RS, Nya-Ngatchou JJ, Liu PY, Amory JK, Leung A, Hull L, Blithe DL, Woo J, Bremner WJ, Wang C.Andrology. 2014 Jul;2(4):579-87. doi: 10.1111/j.2047-2927.2014.00216.x. Epub 2014 May 2. PMID: 24789057 Free PMC Article3:Dimethandrolone undecanoate: a new potent orally active androgen with progestational activity. Attardi BJ, Hild SA, Reel JR.Endocrinology. 2006 Jun;147(6):3016-26. Epub 2006 Feb 23. PMID: 16497801