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PU 02

PU 02

  • CAT Number: I011007
  • CAS Number: 313984-77-9
  • Molecular Formula: C16H12N4S
  • Molecular Weight: 292.36
  • Purity: ≥95%
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PU02（Cat No.:I011007） is a derivative of 6-MP and functions as a negative allosteric modulator of 5-HT3 receptors. It exhibits inhibitory effects on 5-HT3A and 5-HT3AB receptors with measured IC50 values of 0.36 μM and 0.73 μM, respectively, in HEK293 cells after transfection. By modulating the activity of these receptors, PU02 can affect the neurotransmission mediated by serotonin (5-HT), potentially influencing various physiological and pathological processes associated with 5-HT3 receptor signaling.

Catalog Number I011007
CAS Number 313984-77-9
Synonyms

6-[(1-Naphthalenylmethyl)thio]-9H-purine

Molecular Formula

C16H12N4S

Purity 95%
Target 5-HT Receptor
Solubility Soluble to 100 mM in DMSO
Storage 2-8°C
IUPAC Name 6-(naphthalen-1-ylmethylsulfanyl)-7H-purine
InChI InChI=1S/C16H12N4S/c1-2-7-13-11(4-1)5-3-6-12(13)8-21-16-14-15(18-9-17-14)19-10-20-16/h1-7,9-10H,8H2,(H,17,18,19,20)
InChIKey BGMSTNYJYPSLHN-UHFFFAOYSA-N
SMILES C1=CC=C2C(=C1)C=CC=C2CSC3=NC=NC4=C3NC=N4

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