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Psoralen

Psoralen

  • CAT Number: I004520
  • CAS Number: 66-97-7
  • Molecular Formula: C11H6O3
  • Molecular Weight: 186.2
  • Purity: ≥95%
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Psoralen (Cat No.: I004520) is a compound known for its ability to enhance melanin production in the skin. When exposed to ultraviolet light, it can induce a phototoxic reaction and selectively impede DNA synthesis in epidermal cells. Psoralen also demonstrates substantial inhibitory effects on various cancer cell lines, including S180, Ehrlich ascites carcinoma, and liver cancer H-22. This dual action, both in enhancing pigmentation and inhibiting cancer cell growth, underscores its versatility and potential applications in dermatology and oncology.

Catalog Number I004520
CAS Number 66-97-7
Molecular Formula

C11H6O3

Purity 95%
Solubility DMSO: ≥ 1.9 mg/mL
Storage 2-8°C
IUPAC Name furo[3,2-g]chromen-7-one
InChI InChI=1S/C11H6O3/c12-11-2-1-7-5-8-3-4-13-9(8)6-10(7)14-11/h1-6H
InChIKey ZCCUUQDIBDJBTK-UHFFFAOYSA-N
SMILES C1=CC(=O)OC2=CC3=C(C=CO3)C=C21
Reference

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<br>[1]. Xu K, et al. Psoralen activates cartilaginous cellular functions of rat chondrocytes in vitro. Pharm Biol. 2014 Dec 4:1-6.
<br>[2]. Lu H, et al. Isolation and purification of psoralen and isopsoralen and their efficacy and safety in the treatment of osteosarcoma in nude rats. Afr Health Sci. 2014 Sep;14(3):641-7.
<br>[3]. Wu C, et al. Psoralen inhibits bone metastasis of breast cancer in mice. Fitoterapia. 2013 Dec;91:205-10.
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