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PROTAC FLT-3 degrader 1

PROTAC FLT-3 degrader 1

  • CAT Number: I019066
  • CAS Number: 2230826-81-8
  • Molecular Formula: C₅₂H₆₁N₉O₉S₂
  • Molecular Weight: 1020.23
  • Purity: ≥95%
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PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction[1].

Catalog Number I019066
CAS Number 2230826-81-8
Molecular Formula

C₅₂H₆₁N₉O₉S₂

Purity 95%
Reference

[1]. Burslem GM, et al. Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion. J Am Chem Soc. 2018 Dec 5;140(48):16428-16432.

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