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Prostaglandin H2

Prostaglandin H2

  • CAT Number: R065252
  • CAS Number: 42935-17-1
  • Molecular Formula: C20H32O5
  • Molecular Weight: 352.471
  • Purity: ≥95%
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Prostaglandin H<sub>2</sub> (PGH<sub>2</sub>) was first isolated from incubations of arachidonic acid with ovine seminal vesicle microsomes, and was described as a potent vasoconstrictor. PGH<sub>2</sub> is the precursor for all 2-<wbr></wbr>series PGs and thromboxanes (TXs), and is a TP receptor agonist which irreversibly aggregates human platelets at 50-<wbr></wbr>100 ng/ml.

Catalog Number R065252
CAS Number 42935-17-1
Molecular Formula

C20H32O5

Purity 95%
Storage -80°C
IUPAC Name (Z)-7-[(1S,4R,5R,6R)-5-[(E,3S)-3-hydroxyoct-1-enyl]-2,3-dioxabicyclo[2.2.1]heptan-6-yl]hept-5-enoic acid
InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18-14-19(17)25-24-18)10-7-4-5-8-11-20(22)23/h4,7,12-13,15-19,21H,2-3,5-6,8-11,14H2,1H3,(H,22,23)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1
InChIKey YIBNHAJFJUQSRA-YNNPMVKQSA-N
SMILES CCCCCC(C=CC1C2CC(C1CC=CCCCC(=O)O)OO2)O
Reference

1.Hamberg, M.,Svensson, J.,Wakabayashi, T., et al. Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation. Proceedings of the National Academy of Sciences of the United States of America 71, 345-349 (1974).

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