Prostaglandin E2

  • CAT Number: R009261
  • CAS Number: 363-24-6
  • Molecular Formula: C20H32O5
  • Molecular Weight: 352.5
  • Purity: ≥95%
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Dinoprostone has important effects in labour (softening the cervix and causing uterine contraction) and also stimulates osteoblasts to release factors that stimulate bone resorption by osteoclasts.

Catalog Number R009261
CAS Number 363-24-6
Molecular Formula

C20H32O5

Purity 95%
Target Prostanoid Receptors
Solubility Soluble in DMSO > 10 mM
Storage Store at -20C
InChIKey XEYBRNLFEZDVAW-ARSRFYASSA-N
Reference

</br>1:Polysubstituted 4,6-bis(hetero)arylpyrimidines as dual inhibitors of nitric oxide and prostaglandin E2 production. Kolman V, Jansa P, Kalčic F, Janeba Z, Zídek Z.Nitric Oxide. 2017 May 5;67:53-57. doi: 10.1016/j.niox.2017.05.001. [Epub ahead of print] PMID: 28483702 </br>2:Depleted nitric oxide and prostaglandin E2 levels are correlated with endothelial dysfunction in β-thalassemia/HbE patients. Satitthummanid S, Uaprasert N, Songmuang SB, Rojnuckarin P, Tosukhowong P, Sutcharitchan P, Srimahachota S.Int J Hematol. 2017 May 4. doi: 10.1007/s12185-017-2247-8. [Epub ahead of print] PMID: 28474291 </br>3:The Antinociceptive Effect of Light-Emitting Diode Irradiation on Incised Wounds Is Correlated with Changes in Cyclooxygenase 2 Activity, Prostaglandin E2, and Proinflammatory Cytokines. Chia YY, Liu CC, Feng GM, Tseng CA, Hung KC, Chen CC, Tan PH.Pain Res Manag. 2017;2017:4792489. doi: 10.1155/2017/4792489. Epub 2017 Apr 2. PMID: 28469528 Free PMC Article</br>4:Paricalcitol Pretreatment Attenuates Renal Ischemia-Reperfusion Injury via Prostaglandin E2 Receptor EP4 Pathway. Hong YA, Yang KJ, Jung SY, Park KC, Choi H, Oh JM, Lee SJ, Chang YK, Park CW, Yang CW, Kim SY, Hwang HS.Oxid Med Cell Longev. 2017;2017:5031926. doi: 10.1155/2017/5031926. Epub 2017 Mar 29. PMID: 28465762 Free PMC Article</br>5:Impact of cyclooxygenase-2 and prostaglandin-E2 expression on clinical outcome after pulmonary metastasectomy. Lang C, Hrdliczka E, Schweiger T, Glueck O, Lewik G, Schwarz S, Benazzo A, Lang G, Klepetko W, Hoetzenecker K.J Thorac Dis. 2017 Mar;9(3):621-635. doi: 10.21037/jtd.2017.02.83. PMID: 28449470 Free PMC Article</br>6:Adipose-derived mesenchymal stem cells modulate CD14<sup>++</sup>CD16<sup>+</sup> expression on monocytes from sepsis patients in vitro via prostaglandin E2. Qiu G, Zheng G, Ge M, Huang L, Tong H, Chen P, Lai D, Hu Y, Cheng B, Shu Q, Xu J.Stem Cell Res Ther. 2017 Apr 26;8(1):97. doi: 10.1186/s13287-017-0546-x. PMID: 28446249 Free PMC Article</br>7:Prostaglandin E2 produced following infection with Theiler/’s virus promotes the pathogenesis of demyelinating disease. Kim SJ, Jin YH, Kim BS.PLoS One. 2017 Apr 26;12(4):e0176406. doi: 10.1371/journal.pone.0176406. eCollection 2017. PMID: 28445497 Free PMC Article</br>8:Expression of programmed cell death1 in T follicular helper cells is regulated by prostaglandin E2 secreted by HBV-infected HepG2.2.1.5 cells. Sui Z, Shi Y, Gao Z, Yang D, Wang Z.Mol Med Rep. 2017 Jun;15(6):4305-4311. doi: 10.3892/mmr.2017.6503. Epub 2017 Apr 24. PMID: 28440484 </br>9:The double roles of the prostaglandin E2 EP2 receptor in intracerebral hemorrhage. Luo X, Zhu Q, Zhang J, Huang Q, Xie Z, Cheng Y.Curr Drug Targets. 2017 Apr 24. doi: 10.2174/1389450118666170424154248. [Epub ahead of print] PMID: 28440186 </br>10:Immune-Induced Fever Is Dependent on Local But Not Generalized Prostaglandin E2 Synthesis in the Brain. Eskilsson A, Matsuwaki T, Shionoya K, Mirrasekhian E, Zajdel J, Schwaninger M, Engblom D, Blomqvist A.J Neurosci. 2017 May 10;37(19):5035-5044. doi: 10.1523/JNEUROSCI.3846-16.2017. Epub 2017 Apr 24. PMID: 28438967

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