Propyl 4-​Hydroxybenzoate(Propyl Paraben)

• CAT Number: R012953
• CAS Number: 94-13-3
• Molecular Formula: C10H12O3
• Molecular Weight: 180.203
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: propyl 4-hydroxybenzoate
• InChI: InChI=1S/C10H12O3/c1-2-7-13-10(12)8-3-5-9(11)6-4-8/h3-6,11H,2,7H2,1H3
• InChIKey: QELSKZZBTMNZEB-UHFFFAOYSA-N
• SMILES: CCCOC(=O)C1=CC=C(C=C1)O

Propyl 4-Hydroxybenzoate (Propyl Paraben) (Cat No.:R012953) is a p-hydroxybenzoate derivative, mainly used as a bactericidal preservative in food, cosmetics and medicine, and also used as a feed preservative.

Reference

1: Lara-Valderrábano L, Rocha L, Galván EJ. Propylparaben reduces the excitability of hippocampal neurons by blocking sodium channels. Neurotoxicology. 2016 Sep 28;57:183-193. doi: 10.1016/j.neuro.2016.09.019. PubMed PMID: 27693446.2: Qadir MA, Ahmed M, Shafiq MI, Ali A, Sadiq A. Analytical Method for the Identification and Assay of Kojic Acid, Methylparaben, and Propylparaben in Cosmetic Products Using UPLC: Application of ISO 12787:2011 Standard. J AOAC Int. 2016 Sep;99(5):1191-6. doi: 10.5740/jaoacint.16-0026. Epub 2016 Jun 21. PubMed PMID: 27329740.3: Szeląg S, Zabłocka A, Trzeciak K, Drozd A, Baranowska-Bosiacka I, Kolasa A, Goschorska M, Chlubek D, Gutowska I. Propylparaben-induced disruption of energy metabolism in human HepG2 cell line leads to increased synthesis of superoxide anions and apoptosis. Toxicol In Vitro. 2016 Mar;31:30-4. doi: 10.1016/j.tiv.2015.11.011. PubMed PMID: 26616278.4: Roy C, Chakrabarty J. Quality by Design-Based Development of a Stability-Indicating RP-HPLC Method for the Simultaneous Determination of Methylparaben, Propylparaben, Diethylamino Hydroxybenzoyl Hexyl Benzoate, and Octinoxate in Topical Pharmaceutical Formulation. Sci Pharm. 2014 Feb 27;82(3):519-39. doi: 10.3797/scipharm.1312-20. eCollection 2014 Sep. PubMed PMID: 25853065; PubMed Central PMCID: PMC4318166.