Proparacaine Hydrochloride

• CAT Number: A001051
• CAS Number: 5875-06-9
• Molecular Formula: C16H27ClN2O3
• Molecular Weight: 330.85
• Purity: ≥95%
• Synonyms: 5875-06-9; Proparacaine Hcl; Proxymetacaine hydrochloride; Ophthain; 2-(Diethylamino)ethyl 3-Amino-4-propoxybenzoate Hydrochloride
• Target: Sodium Channel
• Solubility: >14.9mg/mL in DMSO
• Storage: -20°C
• InChI: 1S/C16H26N2O3.ClH/c1-4-10-20-15-8-7-13(12-14(15)17)16(19)21-11-9-18(5-2)6-3;/h7-8,12H,4-6,9-11,17H2,1-3H3;1H
• InChIKey: BFUUJUGQJUTPAF-UHFFFAOYSA-N
• SMILES: CCCOC1=C(C=C(C=C1)C(=O)OCCN(CC)CC)N.Cl

Proparacaine Hydrochloride is the hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. It is used as a topical ophthalmic anesthetic. Proparacaine hydrochloride stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting sodium ion influx required for the initiation and conduction of impulses within the neuronal cell, and resulting in a loss of sensation.

Reference

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