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Procarbazine HCl

Procarbazine HCl

  • CAT Number: A000971
  • CAS Number: 366-70-1
  • Molecular Formula: C12H19N3O • HCl
  • Molecular Weight: 257.8
  • Purity: ≥95%
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Procarbazine HCl is a hydrochloride salt form of procarbazine which is a polyfunctional alkylating compound, used for the treatment of Hodgkin/’s lymphoma.<br>Procarbazine plus Cu(II) induce piperidine-labile and formamidopyrimidine-DNA glycosylase-sensitive lesions at the 5/’-ACG-3/’ sequence, complementary to a hotspot of the p53 gene, and the 5/’-TG-3/’ sequence. Procarbazine causes DNA damage through non-enzymatic formation of the Cu(I)-hydroperoxo complex and methyl radicals.<br>Procarbazine causes significant decrease in testicular and epididymal weight and a drastic reduction in haploid cells and spermatogenic arrest, demonstrating variation among the test golden hamster.

Catalog Number A000971
CAS Number 366-70-1
Molecular Formula

C12H19N3O • HCl

Purity 95%
Target DNA Synthesis
Solubility Limited solubility
Storage 3 years -20C powder
InChIKey DERJYEZSLHIUKF-UHFFFAOYSA-N

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