Presatovir

• CAT Number: I001364
• CAS Number: 1353625-73-6
• Molecular Formula: C24H30ClN7O3S
• Molecular Weight: 532.06
• Purity: ≥95%
• Target: RSV
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: N-[2-[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidine-1-carbonyl]-4-chlorophenyl]methanesulfonamide
• InChI: InChI=1S/C24H30ClN7O3S/c1-15-13-32-22(27-23(15)30-10-8-17(26)14-30)12-20(28-32)21-5-3-4-9-31(21)24(33)18-11-16(25)6-7-19(18)29-36(2,34)35/h6-7,11-13,17,21,29H,3-5,8-10,14,26H2,1-2H3/t17-,21-/m0/s1
• InChIKey: GOFXWTVKPWJNGD-UWJYYQICSA-N
• SMILES: CC1=CN2C(=CC(=N2)C3CCCCN3C(=O)C4=C(C=CC(=C4)Cl)NS(=O)(=O)C)N=C1N5CCC(C5)N

Presatovir （Cat No.:I001364） is an antiviral drug that targets the respiratory syncytial virus (RSV), a common virus that causes respiratory infections. It works by inhibiting the fusion of RSV with the host cell, thereby preventing the virus from replicating and causing further damage. Presatovir has shown promising results in preclinical and clinical studies and is currently being evaluated for its efficacy and safety in treating RSV infections.

Reference

[1]. Mackman RL, et al. Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge study. J Med Chem. 2015 Feb 26;58(4):1630-1643.