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PPTN hydrochloride

PPTN hydrochloride

  • CAT Number: I011043
  • Molecular Formula: C29H24F3NO2.HCl
  • Molecular Weight: 511.96
  • Purity: ≥95%
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High affinity and selective P2Y<sub>14</sub> antagonist (K<sub>B</sub> = 434 pM). Exhibits &gt;10,000-fold selectivity for P2Y<sub>14</sub> over other P2Y receptors. Inhibits UDP-glucose and MRS 2690-induced porcine pancreatic artery contraction <em>ex vivo</em>. Also blocks UDP-glucose-induced chemotaxis of HL-60 leukemia cells <em>in vitro</em>.

Catalog Number I011043
Synonyms

4-[4-(4-Piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxylic acid hydrochloride

Molecular Formula

C29H24F3NO2.HCl

Purity 95%
Solubility Soluble to 100 mM in DMSO and to 20 mM in ethanol
Storage Store at -20°C

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