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Plerixafor (AMD3100)

Plerixafor (AMD3100)

  • CAT Number: A000152
  • CAS Number: 110078-46-1
  • Molecular Formula: C28H54N8
  • Molecular Weight: 502.78
  • Purity: ≥95%
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Plerixafor (AMD3100) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively.<br>Plerixafor inhibits CXCL12-mediated chemotaxis with a potency lightly better than its affinity for CXCR4.<br>A single topical application of Plerixafor promotes wound healing in diabetic mice by increasing cytokine production, mobilizing bone marrow EPCs, and enhancing the activity of fibroblasts and monocytes/macrophages, thereby increasing both angiogenesis and vasculogenesis.

Catalog Number A000152
CAS Number 110078-46-1
Synonyms

JM 3100

Molecular Formula

C28H54N8

Purity 95%
Target CXCR
Solubility Limited solubility
Storage 3 years -20C powder

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