Pirepemat fumarate

• CAT Number: I043722
• CAS Number: 2251806-70-7
• Molecular Formula: C15H17F2NO5
• Molecular Weight: 329.30
• Purity: ≥95%
• Synonyms: (E)-but-2-enedioic acid;(3S)-3-(2,3-difluorophenyl)-3-methoxypyrrolidine
• InChI: InChI=1S/C11H13F2NO.C4H4O4/c1-15-11(5-6-14-7-11)8-3-2-4-9(12)10(8)13;5-3(6)1-2-4(7)8/h2-4,14H,5-7H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t11-;/m1./s1
• InChIKey: FHXIIHXNSWGBPV-KGLGULAYSA-N
• SMILES: CO[C@@]1(CCNC1)C2=C(C(=CC=C2)F)F.C(=C/C(=O)O)\C(=O)O

Pirepemat fumarate（Cat No.:I043722）is a novel, selective inhibitor of the voltage-gated sodium channel, used primarily in the treatment of neurological disorders such as epilepsy and neuropathic pain. By blocking the sodium channels, it reduces excessive neuronal firing, which is a hallmark of these conditions. This compound has shown promise in preclinical studies for its ability to modulate excitability in neurons, offering potential therapeutic benefits in managing chronic pain and seizure disorders. Pirepemat fumarate is undergoing clinical trials to assess its efficacy and safety as a treatment option for various neurological conditions.