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GSK3186899

GSK3186899

  • CAT Number: I020012
  • CAS Number: 1972617-87-0
  • Molecular Formula: C₁₉H₂₈F₃N₇O₃S
  • Molecular Weight: 491.53
  • Purity: ≥95%
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GSK3186899 (Cat.No:I020012) is a novel small molecule inhibitor developed by GlaxoSmithKline (GSK). It targets the protein kinase B-Raf, a key component of the MAPK/ERK signaling pathway involved in cell growth and proliferation. GSK3186899 has demonstrated potential as an anti-cancer agent in preclinical studies, particularly in BRAF-mutant tumors. Clinical investigations are underway to evaluate its therapeutic efficacy.

Catalog Number I020012
CAS Number 1972617-87-0
Molecular Formula

C₁₉H₂₈F₃N₇O₃S

Purity 95%
Reference

[1]. Wyllie S, et al. Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis. Nature. 2018 Aug;560(7717):192-197.

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