PI3K/AKT-IN-1

• CAT Number: I043875
• CAS Number: 3033069-84-7
• Molecular Formula: C23H23N5O4S
• Molecular Weight: 465.52
• Purity: ≥95%
• Synonyms: 4-(4-methoxyphenyl)-2-methylsulfanyl-6-[2-[(3,4,5-trimethoxyphenyl)methyl]hydrazinyl]pyrimidine-5-carbonitrile
• IUPAC Name: 4-(4-methoxyphenyl)-2-methylsulfanyl-6-[(2E)-2-[(3,4,5-trimethoxyphenyl)methylidene]hydrazinyl]pyrimidine-5-carbonitrile
• InChI: InChI=1S/C23H23N5O4S/c1-29-16-8-6-15(7-9-16)20-17(12-24)22(27-23(26-20)33-5)28-25-13-14-10-18(30-2)21(32-4)19(11-14)31-3/h6-11,13H,1-5H3,(H,26,27,28)/b25-13+
• InChIKey: WGUUTVSZGSTNKU-DHRITJCHSA-N
• SMILES: COC1=CC=C(C=C1)C2=C(C(=NC(=N2)SC)N/N=C/C3=CC(=C(C(=C3)OC)OC)OC)C#N

PI3K/AKT-IN-1（Cat No.:I043875）is a selective inhibitor targeting the PI3K/AKT signaling pathway, a critical regulator of cell growth, survival, metabolism, and angiogenesis. By inhibiting PI3K and AKT, this compound disrupts the pathway’s downstream effects, which are often dysregulated in various cancers, leading to tumor growth and resistance to apoptosis. PI3K/AKT-IN-1 has shown promise as a potential therapeutic agent for cancer treatment, particularly for tumors with aberrant activation of the PI3K/AKT pathway. It is a valuable tool for preclinical studies aimed at developing targeted therapies for cancer and other diseases.