PI 828

• CAT Number: I010637
• CAS Number: 942289-87-4
• Molecular Formula: C19H18N2O3
• Molecular Weight: 322.36
• Purity: ≥95%
• Target: PI3K
• Solubility: Soluble to 100 mM in DMSO
• Storage: Store at +4°C
• IUPAC Name: 8-(4-aminophenyl)-2-morpholin-4-ylchromen-4-one
• InChI: InChI=1S/C19H18N2O3/c20-14-6-4-13(5-7-14)15-2-1-3-16-17(22)12-18(24-19(15)16)21-8-10-23-11-9-21/h1-7,12H,8-11,20H2
• InChIKey: WUKMIBOGGXMBAC-UHFFFAOYSA-N
• SMILES: C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=C(C=C4)N

PI-828（Cat No.:I010637） is a dual inhibitor targeting both phosphoinositide 3-kinase (PI3K) and casein kinase 2 (CK2). It demonstrates inhibitory activity against p110α, the catalytic subunit of PI3K, with an IC50 value of 173 nM. Additionally, PI-828 inhibits CK2 and its α2 subunit with IC50 values of 149 nM and 1127 nM, respectively. By targeting these key enzymes, PI-828 has the potential to modulate signaling pathways involved in various cellular processes and may serve as a valuable tool in research and therapeutic development.