PHYTANIC ACID

• CAT Number: M059770
• CAS Number: 14721-66-5
• Molecular Formula: C20H40O2
• Molecular Weight: 312.538
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: 3,7,11,15-tetramethylhexadecanoic acid
• InChI: InChI=1S/C20H40O2/c1-16(2)9-6-10-17(3)11-7-12-18(4)13-8-14-19(5)15-20(21)22/h16-19H,6-15H2,1-5H3,(H,21,22)
• InChIKey: RLCKHJSFHOZMDR-UHFFFAOYSA-N
• SMILES: CC(C)CCCC(C)CCCC(C)CCCC(C)CC(=O)O

Phytanic acid is a saturated 20-<wbr></wbr>carbon branched-<wbr></wbr>chain fatty acid which can only be derived from dietary sources. In cases of peroxisomal disorders, elevated levels of phytanic acid have been observed, and this is linked to diseases such as infantile phytanic acid storage disease and Refsum’s disease.

Reference

1. A. Price et al. “Plasma phytanic acid concentration and risk of prostate cancer: results from the European Prospective Investigation into Cancer and Nutrition, Am J Clin Nutr, Vol. 91 pp. 1769-1776, 20102. N. Kruska and G. Reiser “Phytanic acid and pristanic acid, branched-chain fatty acids associated with Refsum disease and other inherited peroxisomal disorders, mediate intracellular Ca2+ signaling through activation of free fatty acid receptor GPR40” Neurobiology of Disease, Vol. 43(2) pp. 465-472, 20113. C. Wolfrum et al. “Phytanic acid is ligand and transcriptional activator of murine liver fatty acid binding protein” JLR, Vol. 40 pp. 708-714, 1999