For research use only. Not for therapeutic Use.
Physalin B（Cat No.:I044872）is a bioactive seco-steroidal compound isolated from plants of the Physalis genus, particularly Physalis angulata. Belonging to the withanolide family, Physalin B features a unique 13,14-seco-ergostane skeleton with multiple oxygenated functional groups. It exhibits a wide range of pharmacological activities, including anti-inflammatory, anticancer, immunosuppressive, and antiparasitic effects. Its mechanisms involve modulation of NF-κB signaling and inhibition of pro-inflammatory cytokines. Due to its potent biological effects, Physalin B is extensively studied for potential therapeutic applications in autoimmune diseases, cancer therapy, and infectious disease management, especially in traditional and integrative medicine research.
| CAS Number | 23133-56-4 |
| Synonyms | (1R,2S,5R,8S,9R,17R,18R,21S,24R,26S,27S)-5-hydroxy-2,9,26-trimethyl-3,19,23,28-tetraoxaoctacyclo[16.9.1.118,27.01,5.02,24.08,17.09,14.021,26]nonacosa-11,14-diene-4,10,22,29-tetrone |
| Molecular Formula | C28H30O9 |
| Purity | ≥95% |
| IUPAC Name | (1R,2S,5R,8S,9R,17R,18R,21S,24R,26S,27S)-5-hydroxy-2,9,26-trimethyl-3,19,23,28-tetraoxaoctacyclo[16.9.1.118,27.01,5.02,24.08,17.09,14.021,26]nonacosa-11,14-diene-4,10,22,29-tetrone |
| InChI | InChI=1S/C28H30O9/c1-23-11-18-25(3)28-19(23)20(30)27(37-28,34-12-16(23)21(31)35-18)15-8-7-13-5-4-6-17(29)24(13,2)14(15)9-10-26(28,33)22(32)36-25/h4,6-7,14-16,18-19,33H,5,8-12H2,1-3H3/t14-,15+,16-,18+,19-,23+,24-,25-,26-,27+,28-/m0/s1 |
| InChIKey | HVTFEHJSUSPQBK-DNJDGUCCSA-N |
| SMILES | C[C@]12C[C@@H]3[C@]4([C@]56[C@H]1C(=O)[C@](O5)([C@@H]7CC=C8CC=CC(=O)[C@@]8([C@H]7CC[C@@]6(C(=O)O4)O)C)OC[C@H]2C(=O)O3)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
