Pentaethylene glycol di(p-toluenesulfonate)

• CAT Number: I016732
• CAS Number: 41024-91-3
• Molecular Formula: C₂₄H₃₄O₁₀S₂
• Molecular Weight: 546.65
• Purity: ≥95%

Pentaethylene glycol di(p-toluenesulfonate) (CAT: I016732) is a versatile PEG-based PROTAC linker specifically designed for use in the synthesis of PROTACs. This linker incorporates pentaethylene glycol to provide flexibility and spacing between the targeting ligand and the E3 ligase ligand. By enabling the controlled conjugation of these two essential components, this linker facilitates the construction of bifunctional molecules that can effectively induce the targeted degradation of specific proteins.

Reference

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.